Antioxidants aid in the removal of residual free radicals that might harm cells and tissue, resulting in fewer inflammatory triggers.
Arthritis is a condition that involves free radicals and inflammation. By reducing free radicals, inflammation may be eased and relieve arthritic pain.
Inflammation can cause many pains besides arthritis. Swelling, pain, localised heat, and redness characterise inflammation. Injury could be a major catalyst for inflammation. When injury occurs, fluid gets trapped in the spaces between cells in the injured tissue. This fluid most often results from leakage from capillaries, but something can also produce directly it in tissue via free radical reactions.
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Besides anti-inflammatory properties, antioxidants like flavonoids may have beneficial effects in arthritic diseases by positively influencing the balance between synthesis and degradation of extra-cellular cartilage constituents. Evidence for this action comes from the inhibition of type II collagen breakdown.
Antioxidants help normalise capillary permeability to prevent the leakage of fluid that causes swelling. It also helps by neutralising free radicals that promote swelling and inflammation. Antioxidants possess multiple anti-inflammatory activities, making it an excellent choice as a natural product in the treatment of inflammatory disorders. These conditions include;
In the acute inflammatory response, the production of this entire battery of free radicals is an important mechanism that is necessary to fight of invading pathogens. However, the problems begin when the inflammatory process persists and becomes chronic, because the inherently high level of oxidative stress turns against the healthy body tissues.
In diseases such as the different arthritis or in autoimmune disorders like lupus or multiple sclerosis, where inflammation manifests chronically, free radicals are permanently produced and can cause tissue destruction. It is in particular in these types of diseases that managing oxidative stress levels should be considered as part of the general therapy.
Evidence for the role of antioxidants in disorders of chronic inflammation comes from many studies on the consequences of the elevated oxidant levels. Biomarkers of cellular damage are indicative of oxidative stress. Antioxidants like flavonoids are uniquely suited as a support or single therapy in the treatment of inflammatory disorders due to their combination of super powerful antioxidant and anti-inflammatory properties.
The reasons to use antioxidants in the management of inflammatory disorders include:
Antioxidants, including flavonoids, are very promising agents for the management of arthritis and other inflammatory diseases. In addition, flavonoids possess multiple anti-inflammatory activities, making it an excellent choice as a support agent in the treatment of inflammatory disorders.